Cell type-specific over-expression of chromosome 21 genes in fibroblasts and fetal hearts with trisomy 21

• Main Authors: Zigman Warren B (Author), Silverman Wayne (Author), Schupf Nicole (Author), Salas Martha (Author), Guo Meirong (Author), Li Chi-Ming (Author), Husain Sameera (Author), Warburton Dorothy (Author), Thaker Harshwardhan (Author), Tycko Benjamin (Author)
• Format: Bog
• Udgivet: BMC, 2006-03-01T00:00:00Z.
• Fag: article
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<p>Abstract</p> <p>Background</p> <p>Down syndrome (DS) is caused by trisomy 21 (+21), but the aberrations in gene expression resulting from this chromosomal aneuploidy are not yet completely understood.</p> <p>Methods</p> <p>We used oligonucleot...