Cell type-specific over-expression of chromosome 21 genes in fibroblasts and fetal hearts with trisomy 21

• Autores principales: Zigman Warren B (Autor), Silverman Wayne (Autor), Schupf Nicole (Autor), Salas Martha (Autor), Guo Meirong (Autor), Li Chi-Ming (Autor), Husain Sameera (Autor), Warburton Dorothy (Autor), Thaker Harshwardhan (Autor), Tycko Benjamin (Autor)
• Formato: Libro
• Publicado: BMC, 2006-03-01T00:00:00Z.
• Materias: article
• Acceso en línea: Connect to this object online.

<p>Abstract</p> <p>Background</p> <p>Down syndrome (DS) is caused by trisomy 21 (+21), but the aberrations in gene expression resulting from this chromosomal aneuploidy are not yet completely understood.</p> <p>Methods</p> <p>We used oligonucleot...