Effects of Perinatal Antibiotic Exposure and Neonatal Gut Microbiota

Antibiotic therapy is one of the most important strategies to treat bacterial infections. The overuse of antibiotics, especially in the perinatal period, is associated with long-lasting negative consequences such as the spread of antibiotic resistance and alterations in the composition and function...

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Main Authors: Chiara Morreale (Author), Cristina Giaroni (Author), Andreina Baj (Author), Laura Folgori (Author), Lucia Barcellini (Author), Amraj Dhami (Author), Massimo Agosti (Author), Ilia Bresesti (Author)
Format: Book
Published: MDPI AG, 2023-01-01T00:00:00Z.
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042 |a dc 
100 1 0 |a Chiara Morreale  |e author 
700 1 0 |a Cristina Giaroni  |e author 
700 1 0 |a Andreina Baj  |e author 
700 1 0 |a Laura Folgori  |e author 
700 1 0 |a Lucia Barcellini  |e author 
700 1 0 |a Amraj Dhami  |e author 
700 1 0 |a Massimo Agosti  |e author 
700 1 0 |a Ilia Bresesti  |e author 
245 0 0 |a Effects of Perinatal Antibiotic Exposure and Neonatal Gut Microbiota 
260 |b MDPI AG,   |c 2023-01-01T00:00:00Z. 
500 |a 10.3390/antibiotics12020258 
500 |a 2079-6382 
520 |a Antibiotic therapy is one of the most important strategies to treat bacterial infections. The overuse of antibiotics, especially in the perinatal period, is associated with long-lasting negative consequences such as the spread of antibiotic resistance and alterations in the composition and function of the gut microbiota, both of which negatively affect human health. In this review, we summarize recent evidence about the influence of antibiotic treatment on the neonatal gut microbiota and the subsequent negative effects on the health of the infant. We also analyze the possible microbiome-based approaches for the re-establishment of healthy microbiota in neonates. 
546 |a EN 
690 |a antibiotic 
690 |a neonate 
690 |a neonatal intensive care unit 
690 |a preterm 
690 |a probiotics 
690 |a gut microbiota 
690 |a Therapeutics. Pharmacology 
690 |a RM1-950 
655 7 |a article  |2 local 
786 0 |n Antibiotics, Vol 12, Iss 2, p 258 (2023) 
787 0 |n https://www.mdpi.com/2079-6382/12/2/258 
787 0 |n https://doaj.org/toc/2079-6382 
856 4 1 |u https://doaj.org/article/b1c5e1d73fad4a7b9f394088223a47b7  |z Connect to this object online.