Dual-target anti-Alzheimer's disease agents with both iron ion chelating and monoamine oxidase-B inhibitory activity
MAO-B leads to an increase in the levels of hydrogen peroxide and oxidative free radicals, which contribute to the aetiology of the AD. Thus, both iron ion chelators and MAO-B inhibitors can be used to treat AD. Taking the coumarin derivatives and hydroxypyridinones as the lead compounds, a series o...
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| Main Authors: | , , , , , , , , , |
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| Format: | Book |
| Published: |
Taylor & Francis Group,
2019-01-01T00:00:00Z.
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