Trehalose Protects against Superoxide Dismutase 1 Proteinopathy in an Amyotrophic Lateral Sclerosis Model
This work aimed to study the effect of trehalose in protecting cells against Sod1 proteinopathy associated with amyotrophic lateral sclerosis (ALS). Humanized yeast cells in which native Sod1 was replaced by wild-type human Sod1 or an ALS mutant (WT-A4V Sod1 heterodimer) were used as the experimenta...
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Main Authors: | Rayne S. S. Magalhães (Author), José R. Monteiro Neto (Author), Gabriela D. Ribeiro (Author), Luan H. Paranhos (Author), Elis C. A. Eleutherio (Author) |
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Format: | Book |
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MDPI AG,
2024-07-01T00:00:00Z.
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