Successful treatment of psychosis in dentatorubral‐pallidoluysian atrophy with quetiapine: A case report

Abstract Introduction Patients with dentatorubral‐pallidoluysian atrophy (DRPLA) sometimes elicit psychosis. First‐generation antipsychotic drugs have been reported to be effective in treating psychotic symptoms associated with the disease. However, little information is available on the benefits of...

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Main Authors: Zui Narita (Author), Tomiki Sumiyoshi (Author)
Format: Book
Published: Wiley, 2018-03-01T00:00:00Z.
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100 1 0 |a Zui Narita  |e author 
700 1 0 |a Tomiki Sumiyoshi  |e author 
245 0 0 |a Successful treatment of psychosis in dentatorubral‐pallidoluysian atrophy with quetiapine: A case report 
260 |b Wiley,   |c 2018-03-01T00:00:00Z. 
500 |a 2574-173X 
500 |a 10.1002/npr2.12005 
520 |a Abstract Introduction Patients with dentatorubral‐pallidoluysian atrophy (DRPLA) sometimes elicit psychosis. First‐generation antipsychotic drugs have been reported to be effective in treating psychotic symptoms associated with the disease. However, little information is available on the benefits of second‐generation antipsychotic drugs (SGAs). Case We report on a 47‐year‐old man with DRPLA whose psychotic symptoms were effectively treated with quetiapine, one of the SGAs. He suffered from delusions, auditory hallucinations, and disorganized speech. Initially, other antipsychotic drugs were tried, but were withdrawn because of adverse effects before switching to quetiapine. Conclusion Our observations add to the notion that some of the SGAs are useful for ameliorating psychosis in DRPLA. 
546 |a EN 
690 |a antipsychotics 
690 |a progressive myoclonic epilepsies 
690 |a psychosis 
690 |a second generation 
690 |a spinocerebellar degenerations 
690 |a Therapeutics. Pharmacology 
690 |a RM1-950 
690 |a Neurosciences. Biological psychiatry. Neuropsychiatry 
690 |a RC321-571 
655 7 |a article  |2 local 
786 0 |n Neuropsychopharmacology Reports, Vol 38, Iss 1, Pp 44-46 (2018) 
787 0 |n https://doi.org/10.1002/npr2.12005 
787 0 |n https://doaj.org/toc/2574-173X 
856 4 1 |u https://doaj.org/article/b1ef5b3787374dae8a89fcc30bd788c8  |z Connect to this object online.