Hybrid Inhibitors of DNA Gyrase A and B: Design, Synthesis and Evaluation
The discovery of multi-targeting ligands of bacterial enzymes is an important strategy to combat rapidly spreading antimicrobial resistance. Bacterial DNA gyrase and topoisomerase IV are validated targets for the development of antibiotics. They can be inhibited at their catalytic sites or at their...
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| Main Authors: | , , , , , , , , , , , , |
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| Format: | Book |
| Published: |
MDPI AG,
2020-12-01T00:00:00Z.
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| Subjects: | |
| Online Access: | Connect to this object online. |
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