ADALIMUMAB IN TREATMENT OF SYSTEMIC JUVENILE IDIOPATHIC ARTHRITIS

A history case of systemic juvenile idiopathic arthritis with early onset and severe clinical case, resistant to treatment with standard immunosuppressive agents is represented in the article. This case demonstrates high clinical efficacy of adalimumab in a patient with severe course of systemic juv...

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Main Authors: R. V. Denisova (Author), E. I. Alexeeva (Author), K. B. Isaeva (Author), T. V. Sleptsova (Author), T. M. Bzarova (Author), S. I. Valieva (Author), E. V. Mitenko (Author), E. G. Chistyakova (Author), A. M. Chomakhidze (Author), A. N. Fetisova (Author), O. L. Lomakina (Author)
Format: Book
Published: "Paediatrician" Publishers LLC, 2013-12-01T00:00:00Z.
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100 1 0 |a R. V. Denisova  |e author 
700 1 0 |a E. I. Alexeeva  |e author 
700 1 0 |a K. B. Isaeva  |e author 
700 1 0 |a T. V. Sleptsova  |e author 
700 1 0 |a T. M. Bzarova  |e author 
700 1 0 |a S. I. Valieva  |e author 
700 1 0 |a E. V. Mitenko  |e author 
700 1 0 |a E. G. Chistyakova  |e author 
700 1 0 |a A. M. Chomakhidze  |e author 
700 1 0 |a A. N. Fetisova  |e author 
700 1 0 |a O. L. Lomakina  |e author 
245 0 0 |a ADALIMUMAB IN TREATMENT OF SYSTEMIC JUVENILE IDIOPATHIC ARTHRITIS 
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500 |a 1682-5527 
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500 |a 10.15690/vsp.v12i6.887 
520 |a A history case of systemic juvenile idiopathic arthritis with early onset and severe clinical case, resistant to treatment with standard immunosuppressive agents is represented in the article. This case demonstrates high clinical efficacy of adalimumab in a patient with severe course of systemic juvenile idiopathic arthritis, prolonged remission of extra-articular involvement and persistent polyarthritis. By the 4th week of the treatment inflammatory changes in the joints had arrested, range of motions had widened, laboratory markers of activity had normalized and non-active stage of the disease had been established. The duration of the remission of articular syndrome was 2 years, no relapses were observed during the follow-up period. 
546 |a EN 
546 |a RU 
690 |a children 
690 |a systemic juvenile idiopathic arthritis 
690 |a adalimumab 
690 |a Pediatrics 
690 |a RJ1-570 
655 7 |a article  |2 local 
786 0 |n Вопросы современной педиатрии, Vol 12, Iss 6, Pp 123-129 (2013) 
787 0 |n https://vsp.spr-journal.ru/jour/article/view/269 
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787 0 |n https://doaj.org/toc/1682-5535 
856 4 1 |u https://doaj.org/article/b22eb9e7007a4b1d8e0c20f5a0bca06b  |z Connect to this object online.