Effect of aging on mitochondria and metabolism of bovine granulosa cells

• Main Authors: Shuta NAGATA (Author), Kaoru TATEMATSU (Author), Kazuki KANSAKU (Author), Yuki INOUE (Author), Mitsuru KOBAYASHI (Author), Koumei SHIRASUNA (Author), Hisataka IWATA (Author)
• Format: Book
• Published: The Society for Reproduction and Development, 2020-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

This study investigated the effect of aging on mitochondria in granulosa cells (GCs) collected from the antral follicles of young and aged cows (25-50 months and over 140 months in age, respectively). When GCs were cultured under 20% O2 for 4 days, mitochondrial DNA copy number (Mt-number), determin...