STANDARISASI PARAMETER NON SPESIFIK DAN PERBANDINGAN KADAR KURKUMIN EKSTRAK ETANOL DAN EKSTRAK TERPURIFIKASI RIMPANG KUNYIT
Turmeric (Curcuma domestica Val.) is one of the plants that contain curcumin compounds with various activity. Use of curcumin from turmeric is widely used in the form of ethanolic extract, but there are ballast substances that cause low levels of curcumin. This can be pursued with the manufacture of...
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| Main Authors: | , |
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| Format: | Book |
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Universitas Ahmad Dahlan,
2013-05-01T00:00:00Z.
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| Summary: | Turmeric (Curcuma domestica Val.) is one of the plants that contain curcumin compounds with various activity. Use of curcumin from turmeric is widely used in the form of ethanolic extract, but there are ballast substances that cause low levels of curcumin. This can be pursued with the manufacture of a purified of ethanolic extract. Ethanolic extract of turmeric was made by maceration using ethanolic 96%. Ethanolic extract soaked with hexane until the hexane phase is clear and purified extract obtained is insoluble hexane phase. Curcumin levels determined using Thin Layer Chromatography (TLC) method with the stationary phase silica gel 60 F and mobile phase of chloroform: ethanolic: glacial acetic acid (94: 5:1) and be analyzed quantitatively using densitometry with a maximum wavelength of 426 nm . The water content of the extract determined using toluene distillation method, ash and acid insoluble ash content determined using gravimetric method. The statistic analysis with LSD showed significant differences of curcumin content and analysis of non-specific parameter values on ethanolic extract and purified extract. |
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| Item Description: | 10.12928/pharmaciana.v3i1.416 2088-4559 2477-0256 |