A permeability‐ and perfusion‐based PBPK model for improved prediction of concentration‐time profiles
Abstract To improve predictions of concentration‐time (C‐t) profiles of drugs, a new physiologically based pharmacokinetic modeling framework (termed 'PermQ') has been developed. This model includes permeability into and out of capillaries, cell membranes, and intracellular lipids. New mod...
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Wiley,
2022-08-01T00:00:00Z.
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