Hyaluronic acid-coated nanoemulsions loaded with a hydrophobic ion pair of all-trans retinoic acid for improving the anticancer activity

• Main Authors: Letícia Márcia da Silva Tinoco (Author), Flávia Lidiane Oliveira da Silva (Author), Lucas Antônio Miranda Ferreira (Author), Elaine Amaral Leite (Author), Guilherme Carneiro (Author)
• Format: Book
• Published: Universidade de São Paulo, 2019-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

All-trans retinoic acid (ATRA) has been studied for the treatment of cancer, including leukemia and breast cancer. This work aims to develop nanoemulsions (NE) loaded with a hydrophobic ion pair (HIP) of all-trans retinoic acid (ATRA) and a lipophilic amine, stearylamine (SA), and coated with hyalur...