Semaphorin 7A promotes endothelial permeability and inflammation via plexin C1 and integrin β1 in Kawasaki disease

• Main Authors: Junhua Huang (Author), Chuanmei Zhao (Author), Shuwan Zhang (Author)
• Format: Bog
• Udgivet: BMC, 2024-04-01T00:00:00Z.
• Fag: article
• Online adgang: Connect to this object online.

Abstract Background Kawasaki disease (KD) is a pediatric systemic vasculitis characterized by endothelial cell dysfunction. Semaphorin 7A (Sema7A) has been reported to regulate endothelial phenotypes associated with cardiovascular diseases, while its role in KD remains unknown. This study aims to in...