Harnessing Clinical Trial and Real-World Data Towards an Understanding of Sex Effects on Drug Pharmacokinetics, Pharmacodynamics and Efficacy

• Những tác giả chính: Joyce Oi Yan Chan (Tác giả), Marie Moullet (Tác giả), Beth Williamson (Tác giả), Rosalinda H. Arends (Tác giả), Venkatesh Pilla Reddy (Tác giả)
• Định dạng: Sách
• Được phát hành: Frontiers Media S.A., 2022-06-01T00:00:00Z.
• Những chủ đề: article
• Truy cập trực tuyến: Connect to this object online.

Increasing clinical data on sex-related differences in drug efficacy and toxicity has highlighted the importance of understanding the impact of sex on drug pharmacokinetics and pharmacodynamics. Intrinsic differences between males and females, such as different CYP enzyme activity, drug transporter...