Choline Kinase α Inhibitors MN58b and RSM932A Enhances the Antitumor Response to Cisplatin in Lung Tumor Cells

• Glavni autori: Juan Carlos Lacal (Autor), Rosario Perona (Autor), Javier de Castro (Autor), Arancha Cebrián (Autor)
• Format: Knjiga
• Izdano: MDPI AG, 2022-05-01T00:00:00Z.
• Teme: article
• Online pristup: Connect to this object online.

Lung cancer is one of the main causes of death in developed countries, and non-small cell lung cancer (NSCLC) is the most frequent type (80% of patients). In advanced NSCLC, platinum-based chemotherapy is the frontline palliative treatment, but less than 5% of patients achieve prolonged survival. Im...