Circulating DNA fragmentomics and cancer screening
Summary: The high fragmentation of nuclear circulating DNA (cirDNA) relies on chromatin organization and protection or packaging within mononucleosomes, the smallest and the most stabilized structure in the bloodstream. The detection of differing size patterns, termed fragmentomics, exploits informa...
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Elsevier,
2023-01-01T00:00:00Z.
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