High-grade transformation of papillary cystadenocarcinoma with p16 immunoreactivity arising from the base of tongue

Papillary cystadenocarcinoma (PCC) is a rare malignant salivary gland neoplasm that accounts for less than 0.2% of primary salivary gland tumors. These tumors are characterized by the presence of invasive cystic and ductal structures and well-defined papillary endophytic projections with or without...

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Bibliographic Details
Main Authors: Katherine Larrabee (Author), Jena C. Patel (Author), Terrance J. Lynn (Author), Iman Sarami (Author), William Quinones (Author)
Format: Book
Published: Elsevier, 2019-06-01T00:00:00Z.
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Summary:Papillary cystadenocarcinoma (PCC) is a rare malignant salivary gland neoplasm that accounts for less than 0.2% of primary salivary gland tumors. These tumors are characterized by the presence of invasive cystic and ductal structures and well-defined papillary endophytic projections with or without mucin production. PCC are generally low-grade indolent tumors with relatively low rate of regional lymph node metastasis. Since malignant tumors are rare, we report a case of papillary cystadenocarcinoma at the base of tongue with focal high-grade transformation and p16 positive immunoreactivity in an 80-year-old male.
Item Description:2214-3300
10.1016/j.ehpc.2019.02.002