Effect of various concentrations of tetracycline hydrochloride demineralization on root dentin surface: A scanning electron microscopic study

Introduction: Within the last 20 years root demineralization has attracted attention as a periodontal regenerative technique. Topical tetracycline application has been widely reported for use as a conditioner, to decontaminate the root surface and to promote periodontal regeneration. The purpose of...

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Main Authors: Tanuja Penmatsa (Author), Satish Varma (Author), Mythili (Author), Killi Prabhakar Rao (Author), Trinath Kishore (Author), Hima Bindu (Author)
Format: Book
Published: Wolters Kluwer Medknow Publications, 2013-01-01T00:00:00Z.
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042 |a dc 
100 1 0 |a Tanuja Penmatsa  |e author 
700 1 0 |a Satish Varma  |e author 
700 1 0 |a Mythili  |e author 
700 1 0 |a Killi Prabhakar Rao  |e author 
700 1 0 |a Trinath Kishore  |e author 
700 1 0 |a Hima Bindu  |e author 
245 0 0 |a Effect of various concentrations of tetracycline hydrochloride demineralization on root dentin surface: A scanning electron microscopic study 
260 |b Wolters Kluwer Medknow Publications,   |c 2013-01-01T00:00:00Z. 
500 |a 0975-7406 
500 |a 0976-4879 
500 |a 10.4103/0975-7406.113296 
520 |a Introduction: Within the last 20 years root demineralization has attracted attention as a periodontal regenerative technique. Topical tetracycline application has been widely reported for use as a conditioner, to decontaminate the root surface and to promote periodontal regeneration. The purpose of this scanning electron microscopic (SEM) study is to evaluate the surface characteristics of demineralized diseased and non-diseased dentine root surfaces using different concentrations of tetracycline hydrochloride (TTC-HCl). Material and Methods: This SEM study was carried out in 20 dentin samples obtained from non-diseased human premolars and 20 dentin samples obtained from diseased human premolars. Pure TTC-HCl was applied to the dentin surface at 50 mg/ml, 100 mg/ml and 150 mg/ml concentrations for 3 min in experimental groups while distilled (0 mg/ml) water was applied to the control groups. Statistical Analysis: Mean and standard deviation were estimated from the sample for each study group. Mean values were compared by either one-way ANOVA with Tukey-Honestly significant difference procedure or Kruskal - Wallis one way ANOVA with Mann-Whitney u-test. Further Student's independent t-test/Mann-Whitney u-test was used appropriately to compare the mean values between two independent groups. Results: In the present study using 100 mg/ml tetracycline seems to be more effective on both diseased and non-diseased dentin surfaces. Conclusions: The results of this study confirm that pure TTC-HCl conditioning produced comparable surface characteristics on dentin of both diseased and non-diseased roots with 100 mg/ml concentration for 3 min. 
546 |a EN 
690 |a Dentine surfaces 
690 |a demineralization 
690 |a root conditioning 
690 |a tetracycline hydrochloride 
690 |a Pharmacy and materia medica 
690 |a RS1-441 
690 |a Analytical chemistry 
690 |a QD71-142 
655 7 |a article  |2 local 
786 0 |n Journal of Pharmacy and Bioallied Sciences, Vol 5, Iss 5, Pp 48-53 (2013) 
787 0 |n http://www.jpbsonline.org/article.asp?issn=0975-7406;year=2013;volume=5;issue=5;spage=48;epage=53;aulast=Penmatsa 
787 0 |n https://doaj.org/toc/0975-7406 
787 0 |n https://doaj.org/toc/0976-4879 
856 4 1 |u https://doaj.org/article/b426f6f10d474c6ea9a82b829c1d49db  |z Connect to this object online.