Cerebral venous sinus thrombosis with meningitis in a child with disseminated staphylococcal disease

• Main Authors: Shalu Gupta (Author), Sanya Chopra (Author)
• Format: Book
• Published: Wolters Kluwer Medknow Publications, 2021-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.
• Notes: 2349-6592; 2455-7099; 10.4103/jpcc.jpcc_164_20
• Keywords: cerebral venous sinus thrombosis; disseminated staphylococcal disease; methicillin-sensitive staphylococcus aureus; Pediatrics; RJ1-570
• Source: Journal of Pediatric Critical Care, Vol 8, Iss 3, Pp 149-152 (2021)

The availability of anti-staphylococcal antibiotics today has revolutionized the treatment strategies to fight Staphylococcus aureus. However, its virulent nature still remains a major cause of morbidity and mortality, especially in the pediatric age group. It presents with a wide spectrum of illnesses ranging from minor skin and soft-tissue infections to fatal necrotizing pneumonia and disseminated disease. However, its presentation as meningitis with septic venous sinus thrombosis in pediatrics remains a rare complication till date. We present the case of an 8-month-old girl child with disseminated staphylococcal disease (DSD) caused by community-acquired methicillin-sensitive S. aureus and complicated by acute mastoiditis, meningitis, and cerebral venous sinus thrombosis. This rare and severe manifestation of DSD was managed successfully with intravenous antibiotics and systemic anticoagulation.