Cloning, purification and characterization of human dentine matrix protein 1(DMP1)

Introduction: Human teeth are composed mainly of dentin, formed by the odontoblasts. Dentin matrix protein 1 (DMP1) is one of odontoblast differentiation's most important growth factors. Human DMP1 has yet to be completely identified or studied. This study aimed to clone and characterize human...

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Main Authors: Tarek El-Bialy (Author), Dror Aizenbud (Author), Hamid Sadeghi (Author), Paul Scott (Author), Itay Aizenbud (Author)
Format: Book
Published: Elsevier, 2023-07-01T00:00:00Z.
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100 1 0 |a Tarek El-Bialy  |e author 
700 1 0 |a Dror Aizenbud  |e author 
700 1 0 |a Hamid Sadeghi  |e author 
700 1 0 |a Paul Scott  |e author 
700 1 0 |a Itay Aizenbud  |e author 
245 0 0 |a Cloning, purification and characterization of human dentine matrix protein 1(DMP1) 
260 |b Elsevier,   |c 2023-07-01T00:00:00Z. 
500 |a 1013-9052 
500 |a 10.1016/j.sdentj.2023.05.006 
520 |a Introduction: Human teeth are composed mainly of dentin, formed by the odontoblasts. Dentin matrix protein 1 (DMP1) is one of odontoblast differentiation's most important growth factors. Human DMP1 has yet to be completely identified or studied. This study aimed to clone and characterize human DMP1. Materials and methods: The DMP1 gene sequence was prepared and cloned by transfection of human 293 cells. Results: The recombinant DMP1 was purified and characterized. Conclusion: The results suggested its future use in dental tissue regeneration and tissue engineering. 
546 |a EN 
690 |a Dentine matrix protein 
690 |a Human 
690 |a Cloning 
690 |a Purification 
690 |a Medicine 
690 |a R 
690 |a Dentistry 
690 |a RK1-715 
655 7 |a article  |2 local 
786 0 |n Saudi Dental Journal, Vol 35, Iss 5, Pp 553-558 (2023) 
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856 4 1 |u https://doaj.org/article/b4cf9a2b847e46618dd48cd9872b9dfd  |z Connect to this object online.