Consequences of drug binding to immune receptors: Immune stimulation following pharmacological interaction with immune receptors (T-cell receptor for antigen or human leukocyte antigen) with altered peptide-human leukocyte antigen or peptide
Drugs may stimulate the immune system by forming hapten-carrier complexes or via their pharmacological features, namely by noncovalent binding to proteins such as immune receptors. The latter type of immune stimulation is called the p-i concept, meaning pharmacological interaction with immune recept...
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Wolters Kluwer Medknow Publications,
2013-12-01T00:00:00Z.
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