Primitive Sca-1 Positive Bone Marrow HSC in Mouse Model of Aplastic Anemia: A Comparative Study through Flowcytometric Analysis and Scanning Electron Microscopy

• Main Authors: Sumanta Chatterjee (Author), Pratima Basak (Author), Prosun Das (Author), Madhurima Das (Author), Jacintha Archana Pereira (Author), Ranjan Kumar Dutta (Author), Malay Chaklader (Author), Samaresh Chaudhuri (Author), Sujata Law (Author)
• Format: Book
• Published: Hindawi Limited, 2010-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Self-renewing Hematopoietic Stem Cells (HSCs) are responsible for reconstitution of all blood cell lineages. Sca-1 is the "stem cell antigen" marker used to identify the primitive murine HSC population, the expression of which decreases upon differentiation to other mature cell types. Sca-...