Acute effects of the resistance exercise associated with different blood flow restriction pressures on bone remodeling biomarkers

• Main Authors: Sedinei Lopes Copatti (Author), Sabrina Lencina Bonorino (Author), Anieli da Costa Copatti (Author), Chrystianne Barros Saretto (Author), Fernando Schorr Grossl (Author), Marzo Edir Da Silva-Grigoletto (Author), Vanessa da Silva Corralo (Author), Clodoaldo Antônio De Sá (Author)
• Format: Book
• Published: Elsevier, 2022-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.
• Notes: 1728-869X; 10.1016/j.jesf.2022.02.005
• Keywords: Exercise therapy; Bone metabolism; Parathyroid hormone; Bone-specific alkaline phosphatase; Resistance exercise; Sports; GV557-1198.995
• Source: Journal of Exercise Science & Fitness, Vol 20, Iss 2, Pp 155-160 (2022)

Background/Objectives: The present study analyzed the acute responses of parathyroid hormone (PTH) and bone-specific alkaline phosphatase (BSAP) to the low-intensity resistance exercise with blood flow restriction using different occlusion pressures. Methods: Twelve women completed the three protocols of this crossover study: resistance exercise without blood flow restriction (RE), resistance exercise with blood flow restriction and occlusion pressure corresponding to 70% of systolic blood pressure (RE + BFR70), and resistance exercise with blood flow restriction and occlusion pressure corresponding 130% of systolic blood pressure (RE + BFR130). All exercises were performed in a guided squat apparatus with load corresponded to 30% of one-repetition maximum test. Results: Relative to resting levels, PTH concentrations decreased significantly (p = .000) post-exercise in all groups and increased significantly (p = .000) 15 min post-exercise in RE + BFR70 and RE + BFR130 groups; PTH concentrations returned to resting levels after the 30-min recovery period in all groups. There was no significant difference (p >.05) between BSAP values at rest and 30 min post-exercise. Conclusion: In conclusion, our results showed that protocols with blood flow restriction using occlusion pressures equivalent to 70% and 130% of systolic blood pressure were more effective than RE alone to induce PTH peaks, and to promote a metabolic condition favorable to bone anabolism.