One-pot and one-step automated radio-synthesis of [18F]AlF-FAPI-74 using a multi purpose synthesizer: a proof-of-concept experiment

• Үндсэн зохиолчид: Sadahiro Naka (Зохиогч), Tadashi Watabe (Зохиогч), Thomas Lindner (Зохиогч), Jens Cardinale (Зохиогч), Kenta Kurimoto (Зохиогч), Melissa Moore (Зохиогч), Mitsuaki Tatsumi (Зохиогч), Yuriko Mori (Зохиогч), Eku Shimosegawa (Зохиогч), Frank Valla (Зохиогч), Hiroki Kato (Зохиогч), Frederik L. Giesel (Зохиогч)
• Формат: Ном
• Хэвлэсэн: SpringerOpen, 2021-08-01T00:00:00Z.
• Нөхцлүүд: article
• Онлайн хандалт: Connect to this object online.

Abstract Background Fibroblast activation protein (FAP) is overexpressed in the stroma of many types of cancer. [18F]AlF-FAPI-74 is a positron emission tomography tracer with high selectivity for FAP, which has already shown high accumulation within human tumors in clinical studies. However, [18F]Al...