One-pot and one-step automated radio-synthesis of [18F]AlF-FAPI-74 using a multi purpose synthesizer: a proof-of-concept experiment

• Главные авторы: Sadahiro Naka (Автор), Tadashi Watabe (Автор), Thomas Lindner (Автор), Jens Cardinale (Автор), Kenta Kurimoto (Автор), Melissa Moore (Автор), Mitsuaki Tatsumi (Автор), Yuriko Mori (Автор), Eku Shimosegawa (Автор), Frank Valla (Автор), Hiroki Kato (Автор), Frederik L. Giesel (Автор)
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• Опубликовано: SpringerOpen, 2021-08-01T00:00:00Z.
• Предметы: article
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Abstract Background Fibroblast activation protein (FAP) is overexpressed in the stroma of many types of cancer. [18F]AlF-FAPI-74 is a positron emission tomography tracer with high selectivity for FAP, which has already shown high accumulation within human tumors in clinical studies. However, [18F]Al...