The promotion action of AURKA on post-ischemic angiogenesis in diabetes-related limb ischemia

• Main Authors: Tao Bai (Author), Mingxing Li (Author), Yuanfeng Liu (Author), Zhentao Qiao (Author), Xusheng Zhang (Author), Yafeng Wang (Author), Zhiwei Wang (Author)
• Format: Book
• Published: BMC, 2023-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Diabetes-related limb ischemia is a challenge for lower extremity amputation. Aurora Kinase A (AURKA) is an essential serine/threonine kinase for mitosis, while its role in limb ischemia remains unclear. Method Human microvascular endothelial cells (HMEC-1) were cultured in high...