Investigation of Liver X Receptor Gene Variants and Oxysterol Dysregulation in Autism Spectrum Disorder

• Main Authors: Tuğba Menteşe Babayiğit (Author), Güvem Gümüş-Akay (Author), Merve Çikili Uytun (Author), Özlem Doğan (Author), Muhittin A. Serdar (Author), Gökçe Yağmur Efendi (Author), Ayşe Gökçe Erman (Author), Esra Yürümez (Author), Didem Behice Öztop (Author)
• 格式: 圖書
• 出版: MDPI AG, 2024-05-01T00:00:00Z.
• 主題: article
• 在線閱讀: Connect to this object online.

The <i>NR1H2</i> gene produces the Liver X Receptor Beta (LXRB) protein, which is crucial for brain cholesterol metabolism and neuronal development. However, its involvement in autism spectrum disorder (ASD) remains largely unexplored, aside from animal studies. This study is the first t...