Nephrotoxicity of cancer therapeutic drugs: Focusing on novel agents

Kidney injury caused by anticancer agents is a common problem that can interfere with and affect the dose intensity of anticancer therapy, thus restricting patient survival. Recent advances in targeted and immunotherapeutic agents have transformed the landscape of medical oncology, and these agents...

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Bibliographic Details
Main Author: Min Hee Hong (Author)
Format: Book
Published: The Korean Society of Nephrology, 2021-09-01T00:00:00Z.
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100 1 0 |a Min Hee Hong  |e author 
245 0 0 |a Nephrotoxicity of cancer therapeutic drugs: Focusing on novel agents 
260 |b The Korean Society of Nephrology,   |c 2021-09-01T00:00:00Z. 
500 |a 2211-9132 
500 |a 2211-9140 
500 |a 10.23876/j.krcp.21.037 
520 |a Kidney injury caused by anticancer agents is a common problem that can interfere with and affect the dose intensity of anticancer therapy, thus restricting patient survival. Recent advances in targeted and immunotherapeutic agents have transformed the landscape of medical oncology, and these agents have been widely employed in clinical practice. While typically associated with favorable toxicity profiles, several novel anticancer drugs present distinctive nephrotoxicities. It remains urgent to closely monitor renal injuries associated with these agents, and medical practitioners should be familiar with general principles for managing nephrotoxicity associated with novel cancer drugs. This review provides an in-depth investigation of the literature and guidelines regarding the prevalence, clinical presentations, mechanisms, and management of nephrotoxicity for each drug. 
546 |a EN 
546 |a KO 
690 |a acute kidney injury 
690 |a immune checkpoint inhibitors 
690 |a molecularly targeted therapy 
690 |a neoplasms 
690 |a renal insufficiency 
690 |a Internal medicine 
690 |a RC31-1245 
690 |a Specialties of internal medicine 
690 |a RC581-951 
655 7 |a article  |2 local 
786 0 |n Kidney Research and Clinical Practice, Vol 40, Iss 3, Pp 344-354 (2021) 
787 0 |n http://www.krcp-ksn.org/upload/pdf/j-krcp-21-037.pdf 
787 0 |n https://doaj.org/toc/2211-9132 
787 0 |n https://doaj.org/toc/2211-9140 
856 4 1 |u https://doaj.org/article/b630ae9fbea545b087bf6c58c6738e0c  |z Connect to this object online.