Angpt2 Induces Mesangial Cell Apoptosis through the MicroRNA-33-5p-SOCS5 Loop in Diabetic Nephropathy

• Autores principales: Yi-Chun Tsai (Autor), Po-Lin Kuo (Autor), Wei-Wen Hung (Autor), Ling-Yu Wu (Autor), Ping-Hsun Wu (Autor), Wei-An Chang (Autor), Mei-Chuan Kuo (Autor), Ya-Ling Hsu (Autor)
• Formato: Libro
• Publicado: Elsevier, 2018-12-01T00:00:00Z.
• Materias: article
• Acceso en línea: Connect to this object online.

Diabetic nephropathy (DN) is the leading cause of end-stage renal disease. Mesangial cell (MC) loss is correlated with worsening renal function in DN. Disturbance of angiopoietin (Angpt)/Tie ligand-receptor system causes inflammation and abnormal angiogenesis. This association between elevated circu...