A Carbon 21 Steroidal Glycoside with Pregnane Skeleton from <em>Cynanchum atratum</em> Bunge Promotes Megakaryocytic and Erythroid Differentiation in Erythroleukemia HEL Cells through Regulating Platelet-Derived Growth Factor Receptor Beta and JAK2/STAT3 Pathway
Erythroleukemia is a rare form of acute myeloid leukemia (AML). Its molecular pathogenesis remains vague, and this disease has no specific therapeutic treatments. Previously, our group isolated a series of Carbon 21 (C-21) steroidal glycosides with pregnane skeleton from the root of <i>Cynanch...
Saved in:
Main Authors: | Jue Yang (Author), Chaolan Pan (Author), Yang Pan (Author), Anlin Hu (Author), Peng Zhao (Author), Meijun Chen (Author), Hui Song (Author), Yanmei Li (Author), Xiaojiang Hao (Author) |
---|---|
Format: | Book |
Published: |
MDPI AG,
2024-05-01T00:00:00Z.
|
Subjects: | |
Online Access: | Connect to this object online. |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
HPLC-UV profiles of Cynanchum auricutalaum, Cynanchum bungei and Cynanchum wilfordii and relationships of their antioxidant activities
by: Pingsu He, et al.
Published: (2023) -
miR-16-5p Promotes Erythroid Maturation of Erythroleukemia Cells by Regulating Ribosome Biogenesis
by: Christos I. Papagiannopoulos, et al.
Published: (2021) -
Cynanchum paniculatum (Bunge) Kitag. ex H.Hara inhibits pancreatic cancer progression by inducing caspase-dependent apoptosis and suppressing TGF-β-mediated epithelial-mesenchymal transition
by: Chien-Shan Cheng, et al.
Published: (2024) -
Childhood acute erythroleukemia diagnosis by flow cytometry
by: Anjali Sharma, et al.
Published: (2011) -
Evaluation of effects of various drugs on platelet functions using phorbol 12-myristate 13-acetate-induced megakaryocytic human erythroid leukemia cells
by: Tada T, et al.
Published: (2016)