METTL3 facilitates immunosurveillance by inhibiting YTHDF2-mediated NLRC5 mRNA degradation in endometrial cancer

• Main Authors: Lei Zhan (Author), Jing Zhang (Author), Jun-Hui Zhang (Author), Xiao-Jing Liu (Author), Bao Guo (Author), Jia-Hua Chen (Author), Zhen-Hai Tang (Author), Wen-Yan Wang (Author), Qing-Yuan Wang (Author), Bing Wei (Author), Yun-Xia Cao (Author)
• Format: Book
• Published: BMC, 2023-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background N6-methyladenosine (m6A) methylation is the most abundant chemical posttranscriptional modification of mRNA, and it is associated with the regulation of the immune response to tumors. However, the function of m6A modification in the immune response to endometrial cancer (EC) rema...