6'-O-Galloylpaeoniflorin Attenuates Osteoclasto-genesis and Relieves Ovariectomy-Induced Osteoporosis by Inhibiting Reactive Oxygen Species and MAPKs/c-Fos/NFATc1 Signaling Pathway

• Main Authors: Wenjie Liu (Author), Gang Xie (Author), Guixin Yuan (Author), Dantao Xie (Author), Zhen Lian (Author), Zihong Lin (Author), Jiajie Ye (Author), Wenyun Zhou (Author), Weijun Zhou (Author), Henghui Li (Author), Xinjia Wang (Author), Haotian Feng (Author), Ying Liu (Author), Guanfeng Yao (Author)
• Format: Book
• Published: Frontiers Media S.A., 2021-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Emerging evidence suggests bright prospects of some natural antioxidants in the treatment of osteoporosis. 6'-O-Galloylpaeoniflorin (GPF), an antioxidant isolated from peony roots (one of very widely used Oriental medicines, with various anti-inflammatory, antitumor, and antioxidant activities)...