Studying synthetic lethal interactions in the zebrafish system: insight into disease genes and mechanisms
The post-genomic era is marked by a pressing need to functionally characterize genes through understanding gene-gene interactions, as well as interactions between biological pathways. Exploiting a phenomenon known as synthetic lethality, in which simultaneous loss of two interacting genes leads to l...
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The Company of Biologists,
2012-01-01T00:00:00Z.
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