Engineering cannabidiol synergistic carbon monoxide nanocomplexes to enhance cancer therapy via excessive autophagy

• Main Authors: Chang Xiao (Author), Yue Sun (Author), Jialong Fan (Author), William Nguyen (Author), Simin Chen (Author), Ying Long (Author), Wei Chen (Author), Aiguo Zhu (Author), Bin Liu (Author)
• Format: Book
• Published: Elsevier, 2023-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Although carbon monoxide (CO)-based treatments have demonstrated the high cancer efficacy by promoting mitochondrial damage and core-region penetrating ability, the efficiency was often compromised by protective autophagy (mitophagy). Herein, cannabidiol (CBD) is integrated into biomimetic carbon mo...