Secretory granule neuroendocrine protein 1 (<it>SGNE1</it>) genetic variation and glucose intolerance in severe childhood and adult obesity

• Main Authors: Charpentier Guillaume (Author), Tichet Jean (Author), Jouret Béatrice (Author), Veslot Jacques (Author), Proença Christine (Author), Heude Barbara (Author), Lecoeur Cécile (Author), Vatin Vincent (Author), Bouatia-Naji Nabila (Author), Marre Michel (Author), Balkau Beverley (Author), Froguel Philippe (Author), Meyre David (Author)
• Format: Book
• Published: BMC, 2007-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

<p>Abstract</p> <p>Background</p> <p>7B2 is a regulator/activator of the prohormone convertase 2 which is involved in the processing of numerous neuropeptides, including insulin, glucagon and pro-opiomelanocortin. We have previously described a suggestive genetic linkag...