Isolation and identification of bioactive compounds in <it>Andrographis paniculata </it>(<it>Chuanxinlian</it>)
<p>Abstract</p> <p><it>Andrographis paniculata </it>(Burm. f.) Nees (Acanthaceae) is a medicinal plant used in many countries. Its major constituents are diterpenoids, flavonoids and polyphenols. Among the single compounds extracted from <it>A. paniculata</it&g...
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| Format: | Book |
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BMC,
2010-05-01T00:00:00Z.
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| Summary: | <p>Abstract</p> <p><it>Andrographis paniculata </it>(Burm. f.) Nees (Acanthaceae) is a medicinal plant used in many countries. Its major constituents are diterpenoids, flavonoids and polyphenols. Among the single compounds extracted from <it>A. paniculata</it>, andrographolide is the major one in terms of bioactive properties and abundance. Among the andrographolide analogues, 14-deoxy-11,12-didehydroandrographolide is immunostimulatory, anti-infective and anti-atherosclerotic; neoandrographolide is anti-inflammatory, anti-infective and anti-hepatotoxic; 14-deoxyandrographolide is immunomodulatory and anti-atherosclerotic. Among the less abundant compounds from <it>A. paniculata</it>, andrograpanin is both anti-inflammatory and anti-infective; 14-deoxy-14,15-dehydroandrographolide is anti-inflammatory; isoandrographolide, 3,19-isopropylideneandrographolide and 14-acetylandrographolide are tumor suppressive; arabinogalactan proteins are anti-hepatotoxic. The four flavonoids from <it>A. paniculata</it>, namely 7-<it>O</it>-methylwogonin, apigenin, onysilin and 3,4-dicaffeoylquinic acid are anti-atherosclerotic.</p> |
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| Item Description: | 10.1186/1749-8546-5-17 1749-8546 |