Protective effects of carbonic anhydrase inhibition in brain ischaemia in vitro and in vivo models

• Үндсэн зохиолчид: Ilaria Dettori (Зохиогч), Irene Fusco (Зохиогч), Irene Bulli (Зохиогч), Lisa Gaviano (Зохиогч), Elisabetta Coppi (Зохиогч), Federica Cherchi (Зохиогч), Martina Venturini (Зохиогч), Lorenzo Di Cesare Mannelli (Зохиогч), Carla Ghelardini (Зохиогч), Alessio Nocentini (Зохиогч), Claudiu T. Supuran (Зохиогч), Anna Maria Pugliese (Зохиогч), Felicita Pedata (Зохиогч)
• Формат: Ном
• Хэвлэсэн: Taylor & Francis Group, 2021-01-01T00:00:00Z.
• Нөхцлүүд: article
• Онлайн хандалт: Connect to this object online.

Ischaemic stroke is a leading cause of death and disability. One of the major pathogenic mechanisms after ischaemia includes the switch to the glycolytic pathway, leading to tissue acidification. Carbonic anhydrase (CA) contributes to pH regulation. A new generation of CA inhibitors, AN11-740 and AN...