Metformin-NSAIDs Molecular Salts: A Path towards Enhanced Oral Bioavailability and Stability

• Main Authors: Francisco Javier Acebedo-Martínez (Author), Alicia Domínguez-Martín (Author), Carolina Alarcón-Payer (Author), Carolina Garcés-Bastida (Author), Cristóbal Verdugo-Escamilla (Author), Jaime Gómez-Morales (Author), Duane Choquesillo-Lazarte (Author)
• Format: Book
• Published: MDPI AG, 2023-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

According to the World Health Organization, more than 422 million people worldwide have diabetes. The most common oral treatment for type 2 diabetes is the drug metformin (MTF), which is usually formulated as a hydrochloride to achieve higher water solubility. However, this drug is also highly hygro...