Anti-hyperuricemia effect of hesperetin is mediated by inhibiting the activity of xanthine oxidase and promoting excretion of uric acid

• Main Authors: Meng-Fei An (Author), Chang Shen (Author), Shao-Shi Zhang (Author), Ming-Yue Wang (Author), Ze-Rui Sun (Author), Mao-Si Fan (Author), Li-Juan Zhang (Author), Yun-Li Zhao (Author), Jun Sheng (Author), Xuan-Jun Wang (Author)
• Format: Book
• Published: Frontiers Media S.A., 2023-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Hesperetin is a natural flavonoid with many biological activities. In view of hyperuricemia treatment, the effects of hesperetin in vivo and in vitro, and the underlying mechanisms, were explored. Hyperuricemia models induced by yeast extract (YE) or potassium oxonate (PO) in mice were created, as w...