Separation of atropisomers by chiral liquid chromatography and thermodynamic analysis of separation mechanism
In the pharmaceutical industry, the analysis of atropisomers is of considerable interest from a scientific and regulatory perspective. The compound of interest contains two stereogenic axes due to the hindered rotation around the single bonds connecting the aryl groups, which results in four potenti...
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| Main Authors: | , , , , |
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| Format: | Book |
| Published: |
Elsevier,
2017-06-01T00:00:00Z.
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