IKK-mediated CYLD phosphorylation and cellular redox activity
Abstract Oxidative stress is important in the development of obesity-related nephropathy (ORN). A causal relationship between IKK and ORN via CYLD-mediated inhibition of NRF2 has been described. However, contradictory explanations about the functioning of the mechanisms that will be effective in the...
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| Format: | Book |
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BMC,
2022-02-01T00:00:00Z.
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| Summary: | Abstract Oxidative stress is important in the development of obesity-related nephropathy (ORN). A causal relationship between IKK and ORN via CYLD-mediated inhibition of NRF2 has been described. However, contradictory explanations about the functioning of the mechanisms that will be effective in the pathogenesis require clarification. |
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| Item Description: | 10.1186/s10020-022-00439-y 1076-1551 1528-3658 |