Simultaneous Imaging and Therapy Using Epitope-Specific Anti-Epidermal Growth Factor Receptor (EGFR) Antibody Conjugates

• المؤلفون الرئيسيون: Anjong Florence Tikum (مؤلف), Anand Krishnan Nambisan (مؤلف), Jessica Pougoue Ketchemen (مؤلف), Hanan Babeker (مؤلف), Musharraf N. Khan (مؤلف), Emina E. Torlakovic (مؤلف), Humphrey Fonge (مؤلف)
• التنسيق: كتاب
• منشور في: MDPI AG, 2022-09-01T00:00:00Z.
• الموضوعات: article
• الوصول للمادة أونلاين: Connect to this object online.

Matuzumab and nimotuzumab are anti-EGFR monoclonal antibodies that bind to different epitopes of domain III of EGFR. We developed ⁸⁹Zr-matuzumab as a PET probe for diagnosis/monitoring of response to treatment of a noncompeting anti-EGFR nimotuzumab antibody drug conjugate (AD...