Nuclear circRNA: Impairing genome stability via circR loops
Abstract Conn et al. have recently reported circRNA: DNA hybrids (circR loops) to promote oncogenic gene translocations and impair genome stability which drive leukemia. Herein, we will summarize potential molecular mechanisms and discuss clinical significance of uncovering circR loops as endogenous...
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| Format: | Book |
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Wiley,
2023-08-01T00:00:00Z.
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| 001 | doaj_b8839c493bb1418e8e68fc1f8f35ebb1 | ||
| 042 | |a dc | ||
| 100 | 1 | 0 | |a Jiao Jiao |e author |
| 700 | 1 | 0 | |a Zhijun Zhang |e author |
| 245 | 0 | 0 | |a Nuclear circRNA: Impairing genome stability via circR loops |
| 260 | |b Wiley, |c 2023-08-01T00:00:00Z. | ||
| 500 | |a 2768-0622 | ||
| 500 | |a 10.1002/ctd2.229 | ||
| 520 | |a Abstract Conn et al. have recently reported circRNA: DNA hybrids (circR loops) to promote oncogenic gene translocations and impair genome stability which drive leukemia. Herein, we will summarize potential molecular mechanisms and discuss clinical significance of uncovering circR loops as endogenous RNA carcinogens. | ||
| 546 | |a EN | ||
| 690 | |a cancer | ||
| 690 | |a circR loop | ||
| 690 | |a circRNA | ||
| 690 | |a genome stability | ||
| 690 | |a Therapeutics. Pharmacology | ||
| 690 | |a RM1-950 | ||
| 655 | 7 | |a article |2 local | |
| 786 | 0 | |n Clinical and Translational Discovery, Vol 3, Iss 4, Pp n/a-n/a (2023) | |
| 787 | 0 | |n https://doi.org/10.1002/ctd2.229 | |
| 787 | 0 | |n https://doaj.org/toc/2768-0622 | |
| 856 | 4 | 1 | |u https://doaj.org/article/b8839c493bb1418e8e68fc1f8f35ebb1 |z Connect to this object online. |