Advanced case of PKDL due to delayed treatment: A rare case report.

Post-kala-azar dermal leishmaniasis (PKDL) is clinical outcome of visceral leishmaniasis (VL) and is thought to be the potential reservoir of parasite. Miltefosine (MF) is the only oral drug existing for treatment of post-kala-azar dermal leishmaniasis (PKDL). Increased miltefosine tolerance in clin...

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Main Authors: Roshan Kamal Topno (Author), Vidya Nand Rabi Das (Author), Maneesh Kumar (Author), Major Madhukar (Author), Krishna Pandey (Author), Neena Verma (Author), Kanhaiya Agrawal (Author), Chandra Shekhar Lal (Author), Niyamat Ali Siddiqui (Author), Sanjiva Bimal (Author), Pradeep Das (Author)
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Published: Public Library of Science (PLoS), 2020-03-01T00:00:00Z.
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042 |a dc 
100 1 0 |a Roshan Kamal Topno  |e author 
700 1 0 |a Vidya Nand Rabi Das  |e author 
700 1 0 |a Maneesh Kumar  |e author 
700 1 0 |a Major Madhukar  |e author 
700 1 0 |a Krishna Pandey  |e author 
700 1 0 |a Neena Verma  |e author 
700 1 0 |a Kanhaiya Agrawal  |e author 
700 1 0 |a Chandra Shekhar Lal  |e author 
700 1 0 |a Niyamat Ali Siddiqui  |e author 
700 1 0 |a Sanjiva Bimal  |e author 
700 1 0 |a Pradeep Das  |e author 
245 0 0 |a Advanced case of PKDL due to delayed treatment: A rare case report. 
260 |b Public Library of Science (PLoS),   |c 2020-03-01T00:00:00Z. 
500 |a 1935-2727 
500 |a 1935-2735 
500 |a 10.1371/journal.pntd.0008052 
520 |a Post-kala-azar dermal leishmaniasis (PKDL) is clinical outcome of visceral leishmaniasis (VL) and is thought to be the potential reservoir of parasite. Miltefosine (MF) is the only oral drug existing for treatment of post-kala-azar dermal leishmaniasis (PKDL). Increased miltefosine tolerance in clinical isolates of Leishmania donovani has been reported and is one of the major concerns in the treatment of PKDL. Here, we report a highly ulcerated PKDL case that was successfully cured after miltefosine treatment. 
546 |a EN 
690 |a Arctic medicine. Tropical medicine 
690 |a RC955-962 
690 |a Public aspects of medicine 
690 |a RA1-1270 
655 7 |a article  |2 local 
786 0 |n PLoS Neglected Tropical Diseases, Vol 14, Iss 3, p e0008052 (2020) 
787 0 |n https://doi.org/10.1371/journal.pntd.0008052 
787 0 |n https://doaj.org/toc/1935-2727 
787 0 |n https://doaj.org/toc/1935-2735 
856 4 1 |u https://doaj.org/article/b88af5d0cffe4b4ea35d04fd5a2cede7  |z Connect to this object online.