Enalapril and Enalaprilat Pharmacokinetics in Children with Heart Failure Due to Dilated Cardiomyopathy and Congestive Heart Failure after Administration of an Orodispersible Enalapril Minitablet (LENA-Studies)

• 主要な著者: Stephanie Laeer (著者), Willi Cawello (著者), Bjoern B. Burckhardt (著者), László Ablonczy (著者), Milica Bajcetic (著者), Johannes M. P. J. Breur (著者), Michiel Dalinghaus (著者), Christoph Male (著者), Saskia N. de Wildt (著者), Jörg Breitkreutz (著者), Muhammed Faisal (著者), Anne Keatley-Clarke (著者), Ingrid Klingmann (著者), Florian B. Lagler (著者)
• フォーマット: 図書
• 出版事項: MDPI AG, 2022-05-01T00:00:00Z.
• 主題: article
• オンライン･アクセス: Connect to this object online.

Angiotensin-converting enzyme inhibitors (ACEI), such as enalapril, are a cornerstone of treatment for pediatric heart failure which is still used off-label. Using a novel age-appropriate formulation of enalapril orodispersible minitablets (ODMTs), phase II/III open-label, multicenter pharmacokineti...