S-Adenosylmethionine and Superoxide Dismutase 1 Synergistically Counteract Alzheimer's Disease Features Progression in TgCRND8 Mice
Recent evidence emphasizes the role of dysregulated one-carbon metabolism in Alzheimer's Disease (AD). Exploiting a nutritional B-vitamin deficiency paradigm, we have previously shown that PSEN1 and BACE1 activity is modulated by one-carbon metabolism, leading to increased amyloid production. W...
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Main Authors: | Rosaria A. Cavallaro (Author), Vincenzina Nicolia (Author), Maria Teresa Fiorenza (Author), Sigfrido Scarpa (Author), Andrea Fuso (Author) |
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Format: | Book |
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MDPI AG,
2017-09-01T00:00:00Z.
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