Itching-like behavior: A common effect of the kappa opioid receptor antagonist 5'-guanidinonaltrindole and the biased kappa opioid receptor agonist 6'-guanidinonaltrindole in mice
Activation of the KOR produces antipruritic effects. In this study, we investigated three KOR ligands for their abilities to cause scratching behaviors in mice, an animal model of itch, and the involvement of the KOR in these behaviors. Two regioisomers are especially interesting: 6'-guanidinon...
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| Main Authors: | , , |
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| Format: | Book |
| Published: |
Elsevier,
2021-09-01T00:00:00Z.
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| Online Access: | Connect to this object online. |
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