Generation of a hTERT-Immortalized Human Sertoli Cell Model to Study Transporter Dynamics at the Blood-Testis Barrier

The blood-testis barrier (BTB) formed by adjacent Sertoli cells (SCs) limits the entry of many chemicals into seminiferous tubules. Differences in rodent and human substrate-transporter selectivity or kinetics can misrepresent conclusions drawn using rodent in vitro models. Therefore, human in vitro...

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Bibliographic Details
Main Authors: Raymond K. Hau (Author), Siennah R. Miller (Author), Stephen H. Wright (Author), Nathan J. Cherrington (Author)
Format: Book
Published: MDPI AG, 2020-10-01T00:00:00Z.
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