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Droplet digital PCR for the quantification of Alu methylation status in hematological malignancies

Abstract Background Alu repeats, belonging to the Short Interspersed Repetitive Elements (SINEs) class, contain about 25% of CpG sites in the human genome. Alu sequences lie in gene-rich regions, so their methylation is an important transcriptional regulation mechanism. Aberrant Alu methylation has...

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Main Authors: Paola Orsini (Author), Luciana Impera (Author), Elisa Parciante (Author), Cosimo Cumbo (Author), Crescenzio F. Minervini (Author), Angela Minervini (Author), Antonella Zagaria (Author), Luisa Anelli (Author), Nicoletta Coccaro (Author), Paola Casieri (Author), Giuseppina Tota (Author), Claudia Brunetti (Author), Alessandra Ricco (Author), Paola Carluccio (Author), Giorgina Specchia (Author), Francesco Albano (Author)
Format: Book
Published: BMC, 2018-12-01T00:00:00Z.
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