Non-surgical management of patients with ectopic pregnancy: A review

An ectopic pregnancy is a medical emergency. Currently, surgery is the main method of therapy, and non-surgical management with methotrexate is considered an acceptable alternative. Methotrexate is a folic acid antagonist and has an inhibitory effect on the proliferation of trophoblast cells. There...

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Main Authors: Yulia E. Dobrokhotova (Author), Tamara N. Belousova (Author), Ekaterina I. Borovkova (Author), Nikolai I. Sovaev (Author), Vera D. Egorushkina (Author), Anastasia D. Kladnitskaya (Author), Anna Ermakova (Author)
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Published: IP Berlin A.V., 2023-12-01T00:00:00Z.
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100 1 0 |a Yulia E. Dobrokhotova  |e author 
700 1 0 |a Tamara N. Belousova  |e author 
700 1 0 |a Ekaterina I. Borovkova  |e author 
700 1 0 |a Nikolai I. Sovaev  |e author 
700 1 0 |a Vera D. Egorushkina  |e author 
700 1 0 |a Anastasia D. Kladnitskaya  |e author 
700 1 0 |a Anna Ermakova  |e author 
245 0 0 |a Non-surgical management of patients with ectopic pregnancy: A review 
260 |b IP Berlin A.V.,   |c 2023-12-01T00:00:00Z. 
500 |a 2079-5696 
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500 |a 10.26442/20795696.2023.4.202518 
520 |a An ectopic pregnancy is a medical emergency. Currently, surgery is the main method of therapy, and non-surgical management with methotrexate is considered an acceptable alternative. Methotrexate is a folic acid antagonist and has an inhibitory effect on the proliferation of trophoblast cells. There are various methotrexate regimens; the choice is based on the level of β-subunit of human chorionic gonadotropin, the location of the ectopic pregnancy and the patient's adherence to treatment. Therapy of ectopic tubal pregnancy with methotrexate is an effective and safe alternative to surgical treatment, does not affect the ovarian reserve and preserves the woman's fertility. 
546 |a RU 
690 |a ectopic tubal pregnancy 
690 |a methotrexate 
690 |a salpingectomy 
690 |a salpingostomy 
690 |a leucovorin 
690 |a trophoblast 
690 |a ovarian reserve 
690 |a Gynecology and obstetrics 
690 |a RG1-991 
655 7 |a article  |2 local 
786 0 |n Гинекология, Vol 25, Iss 4, Pp 435-441 (2023) 
787 0 |n https://gynecology.orscience.ru/2079-5831/article/viewFile/159381/pdf 
787 0 |n https://doaj.org/toc/2079-5696 
787 0 |n https://doaj.org/toc/2079-5831 
856 4 1 |u https://doaj.org/article/b9d97771ef3b45d981458f7d5c6a2db5  |z Connect to this object online.